Elinye igagasi le-COVID-19 eliseduze eFrance: Bangaki Abasazofika?

Kube nokwanda okusheshayo kokuhluka kwe-delta ye-SARS CoV-2 e-France ngoJuni 2021 ngokusekelwe ekuhlaziyweni kwamasampula amahle angama-5061.¹. Amaviki ambalwa alandelayo abaluleke kakhulu mayelana nokuvela kwegagasi lesithathu ngenxa yokudluliseka okuphezulu kokuhluka kwe-delta kanye nomthelela elizoba nawo ohlelweni lokunakekelwa kwezempilo lukahulumeni noluzimele. Ukufa nokugula okuzohlotshaniswa negagasi lesithathu kuzoncika ekusebenzeni kwe-AstraZeneca ChAdOx1 ukugoma, kokuhlukile kwe-delta, enikezwe abantu. 

Ukuhlaziywa kwesibalo sabantu base-UK esithole umthamo wokuqala nowesibili we- I-ChAdOx1 umuthi wokugoma uveza ukuthi ngemva komthamo wokuqala, umgomo wawungasebenzi kahle (33.5% uma uqhathaniswa no-B.1.617.2 [okuhlukile kwe-delta] uma kuqhathaniswa no-51.1% uma kuqhathaniswa nokuhluka kwe-B.1.1.7)². Ukwengeza, ngemva komthamo wesibili futhi, umgomo awuzange usebenze kahle (59.8% uma uqhathaniswa no-B.1.617.2 [okuhlukile kwe-delta] uma kuqhathaniswa no-66.1% uma kuqhathaniswa nokwehluka kwe-B.1.1.7)². 

Kungani sibona amagagasi ahlukene Covid-19 emazweni ahlukahlukene ngezikhathi ezahlukene? Impendulo ingase ibe eqinisweni lokuthi ukuzivikela komhlambi akukafinyeleli futhi “Ukuvalwa thaqa kwezwe" isusiwe okuholela kugagasi elilandelayo le-COVID-19. "Ukuvala phansi" empeleni kuvimbela ukudluliswa kwegciwane futhi ngaleyo ndlela kuvimbele ukuphindaphindeka kwegciwane kanye nokuguquka. Kodwa-ke, inselele ebhekene nayo yiqiniso lokuthi isikhathi ngasinye lapho kufika igagasi, igciwane lithola ithuba lokuzishintsha okungase kuphumele ezinhlobonhlobo ezithathelana kakhulu (uhlobo lwegciwane olunokutheleleka okukhulu okuholela ekubambeleleni ekusindeni kwethiyori enamandla kakhulu), kanjalo ukungawunaki umphumela we ukungafiki komzimba kufinyelelwe ekuhlukeni kwangaphambilini kwegciwane. Muva nje, kuye kwavela okuhlukile okusha okubizwa ngokuthi i-delta plus variant ehlanganisa ukwahluka kwe-delta nokushintshashintsha kwe-K417N (okutholwe okokuqala kwehlukile kwe-Beta eyavela eNingizimu Afrika). Lokhu okuhlukile kwe-delta plus kuyamelana nokwelashwa kwe-antibody. Konke lokhu kubangela inselele enzima mayelana nokuzuza ukuzivikela komhlambi. 

Ukungavikeleki komhlambi³ kusengafinyelelwa uma imithi yokugoma esetshenziswayo inikeza isivikelo esibalulekile okungenani esingaphezu kuka-90% njengoba ifunwa yimithi yokugomela i-mRNA ye-Pfizer neModerna (93.4% enemithamo emi-2 ye-Pfizer ngokumelene nokwehluka kwe-B.1.1.7 kanye no-87.9% ngokumelene i-B.1.617.2 [okuhlukile kwe-delta]). Kodwa-ke, le mithi yokugoma isetshenziswa kakhulu e-USA nase-UK, kanti amanye amazwe ancike kakhulu emuthini wokugoma i-ChAdOx1 (AstraZeneca), umgomo we-Russian Sputnik V kanye nomgomo we-Indian Covaxin. Le mithi yokugoma ingase inikeze noma inganikezeli ukugonywa okusebenzayo ngokumelene nezinhlobonhlobo ezisanda kukhiqizwa. Uma kungekho mithi yokugoma esebenzayo kanye neqiniso lokuthi kukhiqizwa izinhlobo ezintsha ezithathelwana kakhulu cishe ngaso sonke isikhathi lapho igciwane liphindaphinda okuholela ekuguqukeni kwezakhi zofuzo, kungathatha izinyanga ezimbalwa ukufinyelela ukuzivikela komhlambi okufanele futhi amagagasi alandelayo e-COVID-19 azoqhubeka kuze kube umhlambi osebenzayo. ukuzivikela komzimba kufinyelelwa. 

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Okubhekwayo 

1. U-Alizon S., Haim-Boukobza S., et al 2021. Ukusabalala okusheshayo kokuhlukile kwe-SARS-CoV-2 δ endaweni yase-Paris (France) ngoJuni 2021. Kuthunyelwe ngoJuni 20, 2021 kokuthi Preprint medRxiv. I-DOI: https://doi.org/10.1101/2021.06.16.21259052  

2. Bernal JL, Andrews N, Gower C et al. Ukusebenza kwemithi yokugomela i-COVID-19 ngokumelene nokwehluka kwe-B.1.617.2. Kuthunyelwe ngoMeyi 24, 2021. DOI: https://doi.org/10.1101/2021.05.22.21257658 

3. I-Soni R 2021. I-COVID-19: Ukuhlolwa Kokuzivikela Komhlambi kanye Nokuvikelwa Komgomo. Itholakala ku-inthanethi ngo http://scientificeuropean.co.uk/covid-19/covid-19-an-evaluation-of-herd-immunity-and-vaccine-protection/  

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