Ngenxa yokuqubuka kwesifo semonkeypox (Mpox) esibi futhi esikhulayo eDemocratic Republic of the Congo (DRC) manje esesabalale ngaphandle kwezwe nokutholakala kohlobo olusha olwaqala ukuvela ngoSepthemba 2023 ngaphandle kwase-DRC, i-WHO imeme abakhiqizi be Imithi yokugoma ye-mpox yokuhambisa i-Expression of Interest for Emergency Use Listing (EUL) okuhlanganisa idatha yokuqinisekisa ukuthi imigomo iphephile, iyasebenza, yekhwalithi eqinisekisiwe futhi ifanele abantu okuhlosiwe.
Inqubo ye-EUL iyinqubo yokugunyaza ukusetshenziswa kwezimo eziphuthumayo, eyakhelwe ngokukhethekile ukusheshisa ukutholakala kwemikhiqizo yezokwelapha engagunyaziwe njengemithi yokugoma edingekayo ezimeni eziphuthumayo zezempilo yomphakathi. Ukugunyazwa kwe-EUL kuzothuthukisa ukutholakala komuthi wokugoma ikakhulukazi ezilungiselelweni ezinezisetshenziswa ezingakakhiphi imvume yazo yokulawula kazwelonke. I-EUL iphinde inike amandla ozakwethu okuhlanganisa i-Gavi ne-UNICEF ukuthi bathole imigomo ezosatshalaliswa.
I-Monkeypox virus (MPXV) igciwane le-DNA elinemicu ephindwe kabili eliyingxenye ye-Orthopoxvirus kanye ne-vaccinia virus (VACV) kanye ne-variola virus (VARV). Ihlobene eduze nengxibongo, igciwane elibulala kakhulu emlandweni elibangela ukucekelwa phansi okungenakuqhathaniswa kwenani labantu emakhulwini eminyaka adlule. Ngokuqedwa okuphelele kanye nokumiswa okwalandela kohlelo lokugomela ingxibongo (olwalunikeze isivikelo esithile ngokumelene negciwane lemonkeypox), inani labantu lamanje linamazinga anciphe kakhulu okugomela leli qembu lamagciwane. Lokhu kuchaza ngokufanele ukwanda nokusabalala kwamanje kwegciwane lemonkeypox elivela ezindaweni ezihlala kulo e-Afrika.
I-Mpox yisifo esibangelwa yigciwane lemonkeypox. I-Mpox ingadluliselwa kubantu ngokuthintana ngokomzimba nabantu abanaleli gciwane, noma ngezinto ezingcolile, noma nezilwane ezinamagciwane.
Imithi yokugomela i-Mpox esetshenziswayo njengamanje:
Kubantu abadala abanempilo, okungaphindi (MVA-BN), ukuphindaphinda kancane (LC 16) noma ukuphindaphinda imigomo esekelwe kumgomo (ACAM2000) ifanelekile.
I-MVA-BN umuthi wokugomela i-mpox wesizukulwane sesithathu osetshenziswa njengomjovo wemithamo emibili ngaphansi kwesikhumba onikezwa okungenani ngokuhlukana kwamaviki ama-3. Kokubili imithamo engu-4 no-1 ye-MVA-BN iphumelela kakhulu ekuvimbeleni i-mpox.
I-LC16 kanye ne-ACAM2000 umuthi wokugomela i-mpox womthamo owodwa.
***
References:
- Ukukhishwa kwezindaba ze-WHO - I-WHO imema abakhiqizi bomuthi wokugomela i-mpox ukuthi balethe amadosi ukuze ahlolwe isimo esiphuthumayo. Ishicilelwe 09 August 2024. Itholakala e- https://www.who.int/news/item/09-08-2024-who-invites-mpox-vaccine-manufacturers-to-submit-dossiers-for-emergency-evaluations
- I-WHO. Imithi yokugomela imfene: Isiqondiso sesikhashana, 16 November 2022. Itholakala e- https://iris.who.int/bitstream/handle/10665/364527/WHO-MPX-Immunization-2022.3-eng.pdf
- I-Pischel L., et al 2024. Ukusebenza komgomo wokugomela i-mpox yesizukulwane sesi-3 ngokumelene nokuqina kwesifo: Ukubuyekezwa okuhlelekile nokuhlaziywa kwemeta. Umuthi wokugoma. Itholakala ku-inthanethi ngomhla ka-21 Juni 2024. DOI: https://doi.org/10.1016/j.vaccine.2024.06.021
***
Izihloko ezihlobene
I-Virulent Strain of Monkeypox (MPXV) Sabalale Ngokuthintana Ngocansi (20 Ephreli 2024)
Izinhlobo ze-Monkeypox virus (MPXV) ezinikezwe amagama amasha (I-12 Agasti 2022)
Ngabe iMonkeypox izohamba ngendlela yeCorona? (23 Juni 2022)
***
