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I-Ultra-High Fields (UHF) I-MRI Yomuntu: I-Living Brain ifane ne-11.7 Tesla MRI ye-Iseult Project  

Umshini we-Iseult Project we-11.7 Tesla MRI uthathe izithombe ezimangalisayo ze-anatomical bukhoma womuntu ingqondo evela kubahlanganyeli. Lesi isifundo sokuqala bukhoma womuntu Ubuchopho ngomshini we-MRI wamandla kazibuthe aphezulu kangaka oveze izithombe zokulungiswa kwendiza engu-0.2 mm kanye nogqinsi lwesiqephu esingu-1 mm (okumele ivolumu elingana nama-neurons ayizinkulungwane ezimbalwa) ngesikhathi esifushane sokuthola semizuzu emi-4 nje.  

Umfanekiso we womuntu Ubuchopho kulesi sinqumo esingakaze sibonwe ngumshini we-Iseult MRI uzosebenza abacwaningi ukwembula imininingwane emisha yesakhiwo nokusebenza kwe womuntu Ubuchopho okungase kukhanyise indlela ubuchopho obufaka ngayo ukumelwa kwengqondo noma ukuthi yiziphi amasignesha okwazi i-neuronal. Okusha okutholakele kungasiza ekuxilongeni nasekwelapheni iziyaluyalu ze-neurodeergenerative njenge-Alzheimer's kanye ne-Parkinson. Lo mshini ungasiza futhi ekutholeni izinhlobo zamakhemikhali ezihilelekile kumetabolism yobuchopho engeke itholwe ngenye indlela imishini ye-MRI yamandla aphansi kazibuthe.  

Lesi sithwebuli se-11.7 Tesla MRI sephrojekthi ye-Iseult sinamandla kakhulu emhlabeni womuntu umshini we-MRI womzimba wonke futhi ufakwe e-NeuroSpin e-CEA-Paris-Saclay. Yayilethe izithombe zokuqala ngo-2021 lapho ithwebula ithanga futhi yanikeza izithombe ngokulungiswa kwama-microns angama-400 ngezilinganiso ezintathu eziqinisekisa inqubo.  

In womuntu Izinhlelo ze-MRI, amandla kazibuthe ku-7 Tesla noma ngaphezulu kubizwa ngokuthi yi-Ultra-High Fields (UHF). Izikena ze-7 Tesla MRI zagunyazwa ngo-2017 zobuchopho nezithombe ezincane zamalunga. Kunemishini engaphezu kwekhulu ye-T MRI esebenzayo emhlabeni jikelele. Ngaphambi kokuphumelela kwakamuva kwe-7 Tesla MRI scanner ye-Iseult Project, i-11.7 Tesla MRI eNyuvesi yaseMinnesota yayiwumshini we-MRI onamandla kakhulu ekusebenzeni okhiqiza izithombe ze-vivo.  

I-French-German Iseult Project yokwakha isithwebuli se-11.7 Tesla MRI yethulwa yi-French Alternative Energies and Atomic Energy Commission (CEA) ngo-2000. Inhloso bekuwukuthuthukisa 'womuntu umhloli wobuchopho'. Le phrojekthi ihlanganise abalingani bezimboni kanye nezemfundo ndawonye futhi ithathe amashumi amabili eminyaka ukuze ifezeke. Kuyisimangaliso kwezobuchwepheshe futhi kuzoguqula ucwaningo lobuchopho. 

Iqhubekela phambili, inethiwekhi ye-German Ultrahigh Field Imaging (GUFI) isebenzela ukusungula umzimba wonke we-14 Tesla. womuntu Uhlelo lwe-MRI njengesisetshenziswa socwaningo sikazwelonke eJalimane. 

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References:  

  1. I-French Alternative Energies and Atomic Energy Commission (CEA), 2024. Ukukhishwa kwabezindaba – Umboniso wokuqala emhlabeni wonke: ubuchopho obuphilayo bufakwe isithombe esicace ngendlela engenakuqhathaniswa ngenxa yomshini we-MRI onamandla kakhulu emhlabeni. Ishicilelwe ngomhla ka-2 Ephreli 2024. Itholakala e- https://www.cea.fr/english/Pages/News/world-premiere-living-brain-imaged-with-unrivaled-clarity-thanks-to-world-most-powerful-MRI-machine.aspx 
  1. I-Boulant, N., Quettier, L. kanye ne-Iseult Consortium. Ukukhishwa kwe-Iseult CEA 11.7 T ye-MRI yomzimba wonke: isimo samanje, ukuhlolwa kokusebenzisana kwe-gradient-magnet kanye nesipiliyoni sokuqala sokucabanga. I-Magn Reson Mater Phy 36, 175–189 (2023). https://doi.org/10.1007/s10334-023-01063-5  
  1. U-Bihan DL kanye noSchild T., 2017. Human I-MRI yobuchopho ku-500 MHz, imibono yesayensi nezinselele zobuchwepheshe. I-Superconductor Science and Technology, Volume 30, Number 3. DOI: https://doi.org/10.1088/1361-6668/30/3/033003  
  1. Ladd, ME, Quick, HH, Speck, O. et al. Uhambo lwaseJalimane olubheke ku-14 Tesla womuntu i-resonance kazibuthe. I-Magn Reson Mater Phy 36, 191–210 (2023). https://doi.org/10.1007/s10334-023-01085-z  

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Umesh Prasad
Umesh Prasad
Intatheli yesayensi | Umhleli ongumsunguli, umagazini we-Scientific European

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